Potential for Interfraction Esophageal and Tumor Motion to Increase Esophageal Toxicity in Lung SBRT

Potential for Interfraction Motion to Increase Esophageal Toxicity in Lung SBRT

PURPOSE To characterize the effect of the relative motion of esophagus and tumor on radiation doses to the esophagus in patients treated with stereotactic body radiation therapy for central lung tumors. METHODS AND MATERIALS Fifty fractions of stereotactic body radiation therapy in 10 patients with lung tumors within 2.5 cm of the esophagus were reviewed. The esophagus was delineated on each ...

Congenital Esophageal Stenosis Associated with Esophageal Atresia and Gasless Abdomen

SUMMARY A radiologically gasless abdomen in a neonate with EA is usually regarded as being pathognomonic of an absence of distal T.E.F. It has been estimated that up to 1.5% of patient with a distal fistula may have a radiologically gasless abdomens as a manifestation of a very small fistula plugged with mucus. In this case a contrast study via the gastrostomy demonstrated a fistula between th...

Potential biomarkers for esophageal cancer

Esophageal cancer, which consist of esophageal adenocarcinoma and esophageal squamous cell carcinoma, is one of the most common malignant tumors in the world, especially in the south of Iran and China. To find and investigate the biomarkers in the initiation, development and progression of esophageal cancer will help us predict the prognosis of esophageal cancer patients and improve the curativ...

Potential of Proton Therapy to Reduce Acute Hematologic Toxicity in Concurrent Chemoradiation Therapy for Esophageal Cancer

PURPOSE Radiation therapy dose escalation using a simultaneous integrated boost (SIB) is predicted to improve local tumor control in esophageal cancer; however, any increase in acute hematologic toxicity (HT) could limit the predicted improvement in patient outcomes. Proton therapy has been shown to significantly reduce HT in lung cancer patients receiving concurrent chemotherapy. Therefore, we...

Dosimetric Predictors for Acute Esophageal Toxicity